https://reactos.org/node/27385
последний абзац
But Why does it (already) work on Wine?! As it turns out, this is a side-effect of their own hacks. The code of their registry implementation (in the Wine server) allows anybody to create direct subkeys under HKEY_USERS (this is forbidden on a real NT implementation, or in ReactOS, since HKEY_USERS is a virtual registry key, under which real registry keys are loaded), subkeys that are only volatile (are not stored anywhere in a file). As a consequence, when the Word 2010 installation attempts to create/open a subkey under HKEY_USERS\S-1-5-20, even when S-1-5-20 does not exist (and it does not in Wine, since they do not have the special accounts implemented), this key is created on the fly, allowing for the installer to continue its normal route and ultimately succeed. However, as soon as the Word 2010 installer quits (and the Wine server exits), these registry keys just plainly vanish. This fact was confirmed by Sylvain Petreolle. As it may seem acceptable for Wine, this hack is not acceptable at all for ReactOS; we need instead a proper implementation.
Если кратко и по-деревенски, то Вайн «сделан через жопу», его создатели явным образом наплевали на процедуры безопасности заложенные в реальной винде.
